ABSTRACT Most animal-microbe mutualistic associations are characterized by nutrient exchange between the partners.When the host provides the nutrients, it can gain the capacity to shape its microbial community, control the stability of the interaction, and promote its health and fitness.Using the bioluminescent squid-vibrio model, we demonstrate ho
Abstract Background Chimeric antigen receptors (CARs) represent a novel facet of modern day synthetic biology that exemplifies personalized medicine at work through their ability to harness and redirect a patient’s immune system to fight cancer.Body By combining the target-specificity of antibodies to the effector capabilities of T cells, CARs ha
To address the problem of the sparrow search algorithm (SSA) has poor global search ability, weak local development ability, and easily falls into the local optimal solution, a multi-strategy improved evolutionary sparrow search algorithm (MSSA) is proposed.The introduction of the tent chaotic map improves the diversity of the initialization popula
Abstract Background PE lessons are the formal opportunity in schools for promotion of physical activity and fitness.This study aimed to evaluate the effectiveness of a pilot PE intervention on physical activity, fitness, and psychosocial outcomes.Methods Participants were 139 children aged 10–11 years from four schools.For six weeks children in t